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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX11
All Species:
38.79
Human Site:
S219
Identified Species:
65.64
UniProt:
O75558
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75558
NP_003755.2
287
33196
S219
R
E
L
L
R
L
E
S
R
I
R
D
V
H
E
Chimpanzee
Pan troglodytes
XP_001172737
287
33168
S219
R
E
L
L
R
L
E
S
R
I
R
D
V
H
E
Rhesus Macaque
Macaca mulatta
XP_001087826
287
33195
S219
R
E
L
L
R
L
E
S
R
I
R
D
V
H
E
Dog
Lupus familis
XP_854544
287
33311
S219
R
E
L
L
R
L
E
S
R
I
Q
E
V
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3G5
287
33350
G219
R
E
L
L
R
L
E
G
R
I
R
D
V
H
E
Rat
Rattus norvegicus
P50279
290
33341
T208
K
D
I
M
K
L
E
T
S
I
R
E
L
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507707
287
33306
S219
K
E
L
L
K
L
E
S
R
I
R
E
V
H
D
Chicken
Gallus gallus
XP_426154
288
34123
G219
K
E
L
V
K
L
E
G
R
I
K
E
V
H
E
Frog
Xenopus laevis
NP_001086646
285
33430
T217
K
E
L
L
K
L
E
T
R
I
R
E
V
H
D
Zebra Danio
Brachydanio rerio
NP_998075
294
33793
S225
K
E
L
L
E
L
E
S
R
I
R
D
I
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
T210
Q
D
I
M
K
L
E
T
S
I
K
E
L
H
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
S208
N
D
I
M
K
L
E
S
S
I
R
E
L
H
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZQZ8
305
34465
R221
D
T
V
K
E
I
E
R
S
L
L
E
L
H
Q
Baker's Yeast
Sacchar. cerevisiae
P32867
290
33088
K205
Q
E
L
L
K
L
E
K
S
M
A
E
L
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.9
82.5
N.A.
84.6
32
N.A.
75.6
59.3
63.4
51
N.A.
29.2
N.A.
30.2
N.A.
Protein Similarity:
100
99.6
99.6
89.1
N.A.
93.7
57.5
N.A.
88.8
79.1
81.8
70.4
N.A.
54.6
N.A.
53.6
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
93.3
40
N.A.
73.3
60
66.6
73.3
N.A.
26.6
N.A.
40
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
100
93.3
100
86.6
N.A.
93.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
45.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
22
0
0
0
0
0
0
0
0
0
36
0
0
29
% D
% Glu:
0
72
0
0
15
0
100
0
0
0
0
65
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
79
0
% H
% Ile:
0
0
22
0
0
8
0
0
0
86
0
0
8
0
0
% I
% Lys:
36
0
0
8
50
0
0
8
0
0
15
0
0
0
8
% K
% Leu:
0
0
72
65
0
93
0
0
0
8
8
0
36
0
0
% L
% Met:
0
0
0
22
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
8
0
0
0
15
% Q
% Arg:
36
0
0
0
36
0
0
8
65
0
65
0
0
15
0
% R
% Ser:
0
0
0
0
0
0
0
50
36
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
22
0
0
0
0
0
8
0
% T
% Val:
0
0
8
8
0
0
0
0
0
0
0
0
58
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _